Options
Gern, Lise
Nom
Gern, Lise
Affiliation principale
Fonction
Ancien.ne collaborateur.trice
Identifiants
Résultat de la recherche
Voici les éléments 1 - 10 sur 162
- PublicationMétadonnées seulementNatural history of Borrelia burgdorferi sensu lato(1998)
; Humair, Pierre-François - PublicationMétadonnées seulementSeasonality of Ixodes ricinus ticks on vegetation and on rodents and Borrelia burgdorferi sensu lato genospecies diversity in two Lyme borreliosis endemic areas in Switzerland(2012-1-1)
;Pérez, D. ;Kneubühler, Y.; ;Jouda, F. ;Moret, J. - PublicationMétadonnées seulementPrevalence and phylogenetic analysis of tick-borne encephalitis virus (TBEV) in field-collected ticks (Ixodes ricinus) in southern Switzerland(2014)
;Rieille, Nadia ;Bressanelli, Stephane ;Freire, Caio C. M. ;Arcioni, Severine; ; - PublicationMétadonnées seulement
- PublicationMétadonnées seulementTick-borne pathogens in the blood of wild and domestic ungulates in South Africa: interplay of game and livestock(2014)
;Berggoetz, M ;Schmid, M ;Ston, D ;Wyss, V ;Chevillon, Christophe ;Pretorius, A-M - PublicationMétadonnées seulementDo ticks and Borrelia burgdorferi s.l. constitute a burden to birds?(2013-1-1)
;Norte, C.A. ;Lobato, D.C. ;Braga, E. ;Antonelli, Y. ;Lacorte, G. ;Félix, G.M. ;Gonçalves, M. ;Lopes de Carvalho, I.; ;Núncio, M.S.Ramos, J.A. - PublicationAccès libreResolution of experimental and tick-borne Borrelia burgdorferi infection in mice by passive, but not active immunization using recombinant OspC
;Zhong, Weimin; ;Stehle, Thomas ;Museteanu, Crisan ;Kramer, Michael ;Wallich, ReinhardSimon, Markus MVaccination with outer surface protein A (OspA) of Borrelia burgdorferi prevents subsequent infection and disease in both laboratory animals and humans with high efficacy. OspA-based immunity, however, does not affect established infection due to the loss of OspA expression in the vertebrate host. We show here that repeated passive transfer of mouse and/or rabbit immune sera to recombinant GST-OspC fusion protein resulted in a dose-dependent resolution (1) of fully established arthritis and carditis as well as infection in needle-challenged C.B-17 SCID and (2) of infection in both experimentally and tick-infected BALB/c mice. Unexpectedly, active immunization of disease-susceptible AKR/N mice with GST-OspC only led to prevention but not resolution of disease and infection, in spite of high serum titers of OspC-specific Ab and the expression of ospC in tissue-derived spirochetes. The data suggest that the efficacy of OspC antibody-mediated immunity depends on the immunological history of the recipient and/or environment-dependent regulation of OspC surface expression by spirochetes in vivo. The results encourage further attempts to develop therapeutic vaccination protocols against Lyme disease. - PublicationMétadonnées seulement