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Koella, Jacob
Nom
Koella, Jacob
Affiliation principale
Fonction
Professeur.e ordinaire
Email
jacob.koella@unine.ch
Identifiants
Résultat de la recherche
Voici les éléments 1 - 10 sur 10
- PublicationMétadonnées seulementCan transgenic mosquitoes afford the fitness cost?(2008)
;Lambrechts, Louis; Boëte, Christophe - PublicationAccès libreNo maternal effects after stimulation of the melanization response in the yellow fever mosquito Aedes aegypti(2008)
; ;Lambrechts, LouisThe costs and benefits of activating the immune system can reach across generations. Thus, in vertebrates and in several invertebrates, stimulating the immune system of a female can enhance immunity of her offspring or decrease offspring fitness. We evaluated the potential maternally transmitted costs and benefits of the melanization response, an innate immune response of insects that helps to protect mosquitoes from malaria parasites. We manipulated the maternal melanization response of the yellow fever mosquito Aedes aegypti by inoculating female mosquitoes with negatively charged sephadex beads or with immunologically inert glass beads; a control group was not inoculated. In the next generation, we assayed the melanization response and measured three other life-history traits: survival up to emergence, the age at emergence, and body size (estimated as wing length). We found no evidence of fitness costs or benefits for the offspring. A retrospective power analysis found that our experiment would have detected an effect size that is three times smaller than the maternal immune priming effects that have been reported in the literature. We did find a strong correlation between offspring wing length and melanization response. Overall, our findings indicate that trans-generational immune priming in invertebrates cannot be generalized, and that it may depend on the species, the immune challenge, and the environmental conditions. - PublicationMétadonnées seulementEffect of infection by Plasmodium falciparum on the melanization immune response of Anopheles gambiae(2007)
;Lambrechts, Louis ;Morlais, Isabelle ;Awono-Ambene, Parfait H. ;Cohuet, Anna ;Simard, Frédéric ;Jacques, Jean-Claude ;Bourgouin, Catherine - PublicationMétadonnées seulementA major genetic locus controlling natural Plasmodium falciparum infection is shared by East and West African Anopheles gambiae(2007)
;Riehle, Michelle M ;Markianos, Kyriacos ;Lambrechts, Louis ;Xia, Ai ;Sharakhov, Igor; Vernick, Kenneth D. - PublicationMétadonnées seulementEnvironmental influence on the genetic basis of mosquito resistance to malaria parasites(2006)
;Lambrechts, Louis ;Chavatte, Jean-Marc ;Snounou, Georges - PublicationMétadonnées seulementCoevolutionary interactions between host and parasite genotypes(2006)
;Lambrechts, Louis ;Fellous, Simon - PublicationMétadonnées seulementAnopheles gambiae immune responses to Sephadex beads: Involvement of anti-Plasmodium factors in regulating melanization(2006)
;Warr, Emma ;Lambrechts, Louis; ;Bourgouin, CatherineDimopoulos, George - PublicationMétadonnées seulementHost genotype by parasite genotype interactions underlying the resistance of anopheline mosquitoes to Plasmodium falciparum(2005)
;Lambrechts, Louis ;Halbert, Jean ;Durand, Patrick ;Gouagna, Louis Clement - PublicationMétadonnées seulementGenetic correlation between melanization and antibacterial immune responses in a natural population of the malaria vector Anopheles gambiae(2004)
;Lambrechts, Louis ;Vulule, John M.