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Süss-Fink, Georg
Nom
Süss-Fink, Georg
Affiliation principale
Fonction
Professeur ordinaire
Email
georg.suess-fink@unine.ch
Identifiants
Résultat de la recherche
Voici les éléments 1 - 10 sur 25
- PublicationMétadonnées seulementHeteronuclear complexes containing the N,N'-di(2-pyridyl)amidocarboxylferrocene ligand(2012)
; The ferrocene-derived ligand (NC5H4)2NOC-C5H4FeC5H5 reacts with arene ruthenium complexes [(?6-arene)RuCl2]2 to give the cationic complexes [(?6-p-iPrC6H4Me)RuCl{(NC5H4)2NOC-C5H4FeC5H5}]+ (1) and [(?6-C6Me6)RuCl{(NC5H4)2NOC-C5H4FeC5H5}]+ (2), isolated as the hexafluorophosphate and tetrafluoroborate salts, resp., while the reaction with K2PtCl4 yields the neutral complex PtCl2{(NC5H4)2NOC-C5H4FeC5H5} (3). The mol. structures of 2 and 3 were confirmed by single-crystal x-ray diffraction. [on SciFinder(R)] - PublicationMétadonnées seulementDichlorido[1-(2-chloroethyl)-3-(pyridin-4-ylmethyl-?N)urea](?6-hexamethylbenzene)ruthenium(II) chloroform monosolvate(2011)
; The RuII atom in the title compd., [RuCl2(C12H18)(C9H12ClN3O)]·CHCl3, exhibits a typical piano-stool coordination, defined by a hexamethylbenzene ligand, two chloride ligands and a pyridylurea ligand coordinated through the pyridine N atom. In the crystal, a dimeric structure is obsd. due to two strong N-H···Cl interactions between the NH groups of urea and the two chloride ligands of neighboring mols. The C=O group of the urea moiety interacts with the solvent mol. through weak C-H···O interactions. Crystallog. data and at. coordinates are given. [on SciFinder(R)] - PublicationMétadonnées seulementDichlorido[1-(2-chloro-eth-yl)-3-(pyridin-4-ylmethyl-?N)urea](?-hexa-methyl-benzene)-ruthenium(II) chloro-form monosolvate(2011)
; The Ru(II) atom in the title compound, [RuCl(2)(C(12)H(18))(C(9)H(12)ClN(3)O)]?CHCl(3), exhibits a typical piano-stool coordination, defined by a hexa-methyl-benzene ligand, two chloride ligands and a pyridyl-urea ligand coordinated through the pyridine N atom. In the crystal, a dimeric structure is observed due to two strong N-H(midline ellipsis)Cl inter-actions between the NH groups of urea and the two chloride ligands of neighbouring mol-ecules. In addition, the C=O group of the urea moiety inter-acts with the solvent mol-ecule through weak C-H(midline ellipsis)O interactions.[on SciFinder (R)] - PublicationAccès libreDichlorido[1-(2-chloroethyl)-3-(pyridin-4-ylmethyl-κN)urea](η6-hexamethylbenzene)ruthenium(II) chloroform monosolvate(2011)
; The RuII atom in the title compound, [RuCl2(C12H18)(C9H12ClN3O)]•CHCl3, exhibits a typical piano-stool coordination, defined by a hexamethylbenzene ligand, two chloride ligands and a pyridylurea ligand coordinated through the pyridine N atom. In the crystal, a dimeric structure is observed due to two strong N-H...Cl interactions between the NH groups of urea and the two chloride ligands of neighbouring molecules. In addition, the C=O group of the urea moiety interacts with the solvent molecule through weak C-H...O interactions. - PublicationAccès libre[6-(Hydroxymethyl)pyridin-2-yl]methyl ferrocene-1-carboxylate(2011)
; The crystal structure of the title ferrocene derivative, [Fe(C5H5)(C13H12NO3)], shows strong intermolecular O-H...N hydrogen bonds between the alcohol function and the pyridine group of a neighbouring molecule, while the pyridine function forms another hydrogen bond with the alcohol function of another neighbouring molecule, resulting in the formation of chains along the a-axis direction. - PublicationMétadonnées seulementNew dinuclear Ru2(CO)4 sawhorse-type complexes containing bridging carboxylato ligands(2009)
; The thermal reaction of Ru3(CO)12 with ethacrynic acid, 4-[bis(2-chlorethyl)amino]benzenebutanoic acid (chlorambucil), or 4-phenylbutyric acid in refluxing solvents, followed by addn. of 2-electron donor ligands (L), gives the diruthenium complexes Ru2(CO)4(O2CR)2L2 (1: R = CH2O-C6H2Cl2-COC(CH2)C2H5, L = py; 2: R = CH2O-C6H2Cl2-COC(CH2)C2H5, L = PPh3; 3: R = C3H6-C6H4-N(C2H4-Cl)2, L = py; 4: R = C3H6-C6H4-N(C2H4-Cl)2, L = PPh3; 5: R = C3H6-C6H5, L = py; 6: R = C3H6-C6H5, L = PPh3). The single-crystal structure analyses of 2, 3, 5, and 6 reveal a dinuclear Ru2(CO)4 sawhorse structure, the diruthenium backbone being bridged by the carboxylato ligands, while the 2 L ligands occupy the axial positions of the diruthenium unit. [on SciFinder(R)] - PublicationMétadonnées seulementArene-ruthenium complexes with ferrocene-derived ligands: Synthesis and characterization of complexes of the type [Ru(?6-arene)(NC5H4CH2NHOC-C5H4FeC5H5)Cl2] and [Ru(?6-arene)(NC3H3N(CH2)2O2C-C5H4FeC5H5)Cl2](2009)
; ; - PublicationAccès libreArene–ruthenium complexes with ferrocene-derived ligands: Synthesis and characterization of complexes of the type [Ru(η6-arene)(NC5H4CH2NHOC-C5H4FeC5H5)Cl2] and [Ru(η6-arene)(NC3H3N(CH2)2O2C–C5H4FeC5H5)Cl2](2009)
; ; - PublicationAccès libreSawhorse-type diruthenium tetracarbonyl complexes containing porphyrin-derived ligands as highly selective photosensitizers for female reproductive cancer cells(2009)
; ; Juillerat-Jeanneret, LucienneDiruthenium tetracarbonyl complexes of the type [Ru2 (CO)4(μ2-η2-O2CR)2L2] containing a Ru–Ru backbone with four equatorial carbonyl ligands, two carboxylato bridges, and two axial two-electron ligands in a sawhorse-like geometry have been synthesized with porphyrin-derived substituents in the axial ligands [1: R is CH3, L is 5-(4-pyridyl)-10,15,20-triphenyl-21,23H-porphyrin], in the bridging carboxylato ligands [2: RCO2H is 5-(4-carboxyphenyl)-10,15,20-triphenyl-21,23H-porphyrin, L is PPh3; 3: RCO2H is 5-(4-carboxyphenyl)-10,15,20-triphenyl-21,23H-porphyrin, L is 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane], or in both positions [4: RCO2H is 5-(4-carboxyphenyl)-10,15,20-triphenyl-21,23H-porphyrin, L is 5-(4-pyridyl)-10,15,20-triphenyl-21,23H-porphyrin]. Compounds 1–3 were assessed on different types of human cancer cells and normal cells. Their uptake by cells was quantified by fluorescence and checked by fluorescence microscopy. These compounds were taken up by human HeLa cervix and A2780 and Ovcar ovarian carcinoma cells but not by normal cells and other cancer cell lines (A549 pulmonary, Me300 melanoma, PC3 and LnCap prostate, KB head and neck, MDAMB231 and MCF7 breast, or HT29 colon cancer cells). The compounds demonstrated no cytotoxicity in the absence of laser irradiation but exhibited good phototoxicities in HeLa and A2780 cells when exposed to laser light at 652 nm, displaying an LD50 between 1.5 and 6.5 J/cm2 in these two cell lines and more than 15 J/cm2 for the others. Thus, these types of porphyric compound present specificity for cancer cell lines of the female reproductive system and not for normal cells; thus being promising new organometallic photosensitizers. - PublicationAccès libreSawhorse-type diruthenium tetracarbonyl complexes containing porphyrin-derived ligands as highly selective photosensitizers for female reproductive cancer cells(2009)
; ; Juillerat-Jeanneret, LucienneDiruthenium tetracarbonyl complexes of the type [Ru2(CO)4(?2-?2-O2CR)2L2] contg. a Ru-Ru backbone with four equatorial carbonyl ligands, two carboxylato bridges, and two axial two-electron ligands in a sawhorse-like geometry have been synthesized with porphyrin-derived substituents in the axial ligands [1: R is CH3, L is 5-(4-pyridyl)-10,15,20-triphenyl-21,23H-porphyrin], in the bridging carboxylato ligands [2: RCO2H is 5-(4-carboxyphenyl)-10,15,20-triphenyl-21,23H-porphyrin, L is PPh3; 3: RCO2H is 5-(4-carboxyphenyl)-10,15,20-triphenyl-21,23H-porphyrin, L is 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane], or in both positions [4: RCO2H is 5-(4-carboxyphenyl)-10,15,20-triphenyl-21,23H-porphyrin, L is 5-(4-pyridyl)-10,15,20-triphenyl-21,23H-porphyrin]. Compds. 1-3 were assessed on different types of human cancer cells and normal cells. Their uptake by cells was quantified by fluorescence and checked by fluorescence microscopy. These compds. were taken up by human HeLa cervix and A2780 and Ovcar ovarian carcinoma cells but not by normal cells and other cancer cell lines (A549 pulmonary, Me300 melanoma, PC3 and LnCap prostate, KB head and neck, MDAMB231 and MCF7 breast, or HT29 colon cancer cells). The compds. demonstrated no cytotoxicity in the absence of laser irradn. but exhibited good phototoxicities in HeLa and A2780 cells when exposed to laser light at 652 nm, displaying an LD50 between 1.5 and 6.5 J/cm2 in these two cell lines and more than 15 J/cm2 for the others. Thus, these types of porphyric compd. present specificity for cancer cell lines of the female reproductive system and not for normal cells; thus being promising new organometallic photosensitizers. [on SciFinder(R)]
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