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Microfabrication and characterization of an ion-selective microelectrode array platform
Auteur(s)
Guenat, Olivier T.
Dufour, J.-F.
van der Wal, P.D.
Morf, Werner E.
de Rooij, Nicolaas F.
Koudelka-Hep, Milena
Date de parution
2005
In
Sensors and Actuators B : Chemical, Elsevier, 2005/105/1/65-73
Résumé
The design and the fabrication of an ion-selective electrode array platform aimed at in vitro intracellular recording are presented. The platform is composed of two parts: (i) a glass chip with microchannels whose bottom part is patterned with a platinum layer and (ii) a silicon chip in which an array of 50 μm long silicon nitride micropipettes with an inner diameter of 5 μm are structured. The 24 micropipettes are individually filled with a Ca<sup>2+</sup> selective membrane, based on the neutral ionophore ETH 129. Preliminary tests in Ca<sup>2+</sup> buffered solutions have shown a linear range from 10<sup>−6</sup> to 0.1 M Ca<sup>2+</sup> with a sensitivity of 27 mV/decade.
Identifiants
Type de publication
journal article
