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Inhibition of porphobilinogen synthase (PBG-synthase) by 4,6-dioxoheptanoic acid and related compounds
Auteur(s)
Stauffer, Frederic
Jarret, Caroline
Engeloch, Thomas
Henz, Matthias
Bobalova, Janette
Date de parution
1998
In
ECHET98 Electron. Conf. Heterocycl. Chem.
De la page
459
A la page
465
Résumé
We are investigating the mechanism of PBG-synthase by active site directed inhibition studies. The procedure for testing and the data obtained with compds. related to 4,6-dioxoheptanoic acid are reported and the results are discussed in the context of our kinetic model. [on SciFinder(R)]
Identifiants
Type de publication
journal article
