Options
Ru<sub>2</sub>(CO)<sub>4</sub>(OOCR)<sub>2</sub>(PPh<sub>3</sub>)<sub>2</sub> sawhorse-type complexes containing μ<sub>2</sub>-η<sup>2</sup>-carboxylato ligands derived from biologically active acids
Auteur(s)
Date de parution
2006
In
Inorganica Chimica Acta, Elsevier, 2006/359/1/3412-3416
Résumé
The thermal reaction of Ru<sub>3</sub>(CO)<sub>12</sub> with the biologically active acids acetyl salicylic acid (Aspirin), α-methyl-4-(isobutyl)phenylacetic acid (Ibuprofen) and 3α,7α,12α-trihydroxy-5β-cholanic acid (cholic acid) in refluxing tetrahydrofuran, followed by addition of triphenylphosphine, gives the dinuclear complexes Ru<sub>2</sub> (CO) <sub>4</sub>(OOCR)<sub>2</sub>(PPh<sub>3</sub>)<sub>2</sub> (<b>1</b>: R = C<sub>6</sub>H<sub>4</sub>-2-OCOMe, <b>2</b>: R = CHMe-C<sub>6</sub>H<sub>4</sub>-4-Bu<sup>i</sup>, <b>3</b>: C<sub>23</sub>H<sub>39</sub>O<sub>3</sub>). The single-crystal structural analysis of <b>1</b> and <b>2</b> reveals a dinuclear Ru<sub>2</sub>(CO)<sub>4</sub> sawhorse structure, the diruthenium backbone being bridged by the carboxylato ligands, while the two phosphine ligands occupy the axial positions at the ruthenium atoms. However, chiral carbon atoms in the carboxylic acid undergo racemisation during the thermal reaction.
Identifiants
Type de publication
journal article
Dossier(s) à télécharger
