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  4. Transmission of Borrelia garinii OspA serotype 4 to BALB/c mice by Ixodes ricinus ticks collected in the field
 
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Transmission of Borrelia garinii OspA serotype 4 to BALB/c mice by Ixodes ricinus ticks collected in the field

Auteur(s)
Hu, Chang Min
Wilske, Bettina
Fingerle, Volker
Lobet, Yves
Gern, Lise 
Institut de biologie 
Date de parution
2001
In
Journal of Clinical Microbiology
Vol.
3
No
39
De la page
1169
A la page
1171
Mots-clés
  • BURGDORFERI SENSU-LAT...

  • LYME BORRELIOSIS

  • SP-NOV

  • SEQUENCE-ANALYSIS

  • MONOCLONAL-ANTIBODIES...

  • CEREBROSPINAL-FLUID

  • DIVERSITY

  • AFZELII

  • DISEASE

  • STRICTO

Résumé
In Europe, Borrelia garinii OspA serotype 4 has been isolated from the cerebrospinal fluid of patients but, up to now, has never been identified among culture isolates from Ixodes ricinus ticks. This information raises the question of whether OspA serotype 4 is transmitted by I. ricinus in nature. In the present study, L ricinus nymphs collected in an area of endemicity in southern Germany were allowed to feed on mice. Cultivation of ear biopsy specimens showed that six of seven B. garinii-infected mice were infected by OspA serotype 4. In contrast, very few B. garinii OspA serotype 4 organisms were isolated directly from the ticks which infected the mice; most isolates were B. afzelii. The infected mice transmitted mainly OspA serotype 4 to xenodiagnostic ticks, preferentially in combination with B. afzelii.
Identifiants
https://libra.unine.ch/handle/123456789/11769
Type de publication
journal article
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