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  4. Antibacterial triterpenes from <i>Syzygium guineense</i> (Myrtaceae)
 
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Antibacterial triterpenes from <i>Syzygium guineense</i> (Myrtaceae)

Auteur(s)
Djoukeng, J.D.
Editeur(s)
Abou-Mansour, Eliane
Tabacchi, Raphaël
Tapondjou, A.L.
Bouda, H.
Lontsi, D.
Date de parution
2005
In
Journal of Ethnopharmacology, Elsevier, 2005/101/1-3/283-286
Mots-clés
  • Syzygium guineense

  • Triterpenes

  • Antibacterial activit...

Résumé
Antibacterial bioassay-guided fractionation of <i>Syzygium guineense</i> leaf extracts afforded 10 triterpenes, namely betulinic acid <b>1</b>, oleanolic acid <b>2</b>, a mixture of 2-hydroxyoleanolic acid <b>3a</b>, 2-hydroxyursolic acid <b>3b</b>, arjunolic acid <b>4a</b>, asiatic acid <b>4b</b>, a mixture of terminolic acid <b>5a</b>, 6-hydroxyasiatic acid <b>5b</b>, and a mixture of arjunolic acid 28-β-glucopyranosyl ester <b>6a</b> and the asiatic acid 28-β-glucopyranosyl ester 6b. Isolated compounds were submitted to an antibacterial assay system against gram-positive and -negative bacteria and human pathogen bacteria. Compounds <b>4a</b> and <b>4b</b> showed the most significant antibacterial activity against <i>Escherichia coli</i>, <i>Bacillus subtilis</i> and <i>Shigella sonnei</i>. The fraction <b>5a–5b</b> was the least active, whereas compounds <b>1, 2</b> and the mixtures of <b>3a–3b</b> and <b>6a–6b</b> were inactive in the assays.
URI
https://libra.unine.ch/handle/123456789/15393
DOI
10.1016/j.jep.2005.05.008
Autre version
http://dx.doi.org/10.1016/j.jep.2005.05.008
Type de publication
Resource Types::text::journal::journal article
Dossier(s) à télécharger
 main article: Tabacchi_R._-_Antibacterial_triterpenes_from_Syzygium_20090512.pdf (331.86 KB)
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