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Aeschlimann, André

Nom
Aeschlimann, André
Affiliation principale
Fonction
Professeur honoraire
Email
audrey.aeschlimann@unine.ch
Identifiants
https://libra.unine.ch/handle/123456789/348

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  • Publication
    Accès libre
    Erythema chronicum migrans – a tickborne spirochetosis
    (1986)
    Burgdorfer, Willy
    ;
    Barbour, Alan G.
    ;
    Hayes, Stanley F.
    ;
    Péter, Olivier
    ;
    Aeschlimann, André 
  • Publication
    Accès libre
    Erythma chronicum migrans a tickborne – a tickborne spirochetosis. Short communication
    (1983)
    Burgdorfer, Willy
    ;
    Barbour, Alan G.
    ;
    Hayes, Stanley F.
    ;
    Péter, Olivier
    ;
    Aeschlimann, André 
  • Publication
    Accès libre
    Isolation of a cultivable spirochete from Ixodes ricinus ticks of Switzerland
    (1983)
    Barbour, Alan G.
    ;
    Burgdorfer, Willy
    ;
    Hayes, Stanley F.
    ;
    Péter, Olivier
    ;
    Aeschlimann, André 
    We have isolated in BSK medium a spirochete of Ixodes ricinus ticks. The ticks were collected from an area of Switzerland where erythema chronicum migrans, a tick-borne, penicillin-ameliorated inflammatory disorder, is endemic. The I. ricinus spirochete was very similar in its morphology, polyacrylamide-gel-electrophoresis profile, and antigenic determinants to a spirochete that was previously isolated from Ixodes dammini ticks of the United States.
  • Publication
    Accès libre
    Ixodes ricinus : vector of a hitherto undescribed spotted fever group agent in Switzerland
    (1979)
    Burgdorfer, Willy
    ;
    Barbour, Alan G.
    ;
    Hayes, Stanley F.
    ;
    Péter, Olivier
    ;
    Aeschlimann, André 
    A tick/rickettsial survey in various parts of Switzerland revealed the presence of a new, hitherto undescribed spotted fever group rickettsia ("Swiss agent") in up to 11.7% of I ricinus collected off vegetation. Infection in ticks was found to be generalized with rickettsiae developing intracellularly and occasionally also intranuclearly. As a result of massive growth in ovarial tissues, including the germinative cells, the rate oftransovarial and filial infection was 100%.
    The "Swiss agent" appears to be nonpathogenic for guinea pigs, domestic rabbits, and Swiss mice, but in male meadow voles (Microtus pennsylvanicus) it produces a microscopically detectable infection in the tunica vaginalis. The rickettsia grows well in tissue culture systems including chick embryo fibroblast, Vero, and vole tissue cells, when inoculated via yolk sac into 5-day-old hens' eggs, it kills 100% of the embryos after 5 to 7 days.
    Antigenic relatedness of the "Swiss agent" to rickettsiae of the spotted fever group was indicated by indirect and direct fluorescent antibody staining. Preliminary serologic typing by microimmunofluorescence and by microagglutination indicated that the "Swiss agent" differs from all prototype strains of spotted fever group rickettsiae studied so far.