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Aeschlimann, André

Nom
Aeschlimann, André
Affiliation principale
Fonction
Professeur honoraire
Email
audrey.aeschlimann@unine.ch
Identifiants
https://libra.unine.ch/handle/123456789/348

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  • Publication
    Accès libre
    Erythema chronicum migrans – a tickborne spirochetosis
    (1986)
    Burgdorfer, Willy
    ;
    Barbour, Alan G.
    ;
    Hayes, Stanley F.
    ;
    Péter, Olivier
    ;
    Aeschlimann, André 
  • Publication
    Accès libre
    Erythma chronicum migrans a tickborne – a tickborne spirochetosis. Short communication
    (1983)
    Burgdorfer, Willy
    ;
    Barbour, Alan G.
    ;
    Hayes, Stanley F.
    ;
    Péter, Olivier
    ;
    Aeschlimann, André 
  • Publication
    Accès libre
    The peritrophic membrane of Ixodes ricinus
    (1991)
    Zhu, Z.
    ;
    Gern, Lise 
    ;
    Aeschlimann, André 
    A peritrophic membrane was found in all three stages of Ixodes ricinus at no later than 18 h after their placement on rabbits. It was found to remain intact until at least 11, 30 and 10 days after repletion in larvae, nymphs and females, respectively. In blood-feeding I. ricinus, the peritrophic membrane is an uneven single layer with a thickness of about 0.03–0.48 μm in larvae, 0.03–0.79 μm in nymphs and 0.04–0.93 μm in females. It covers the whole surface of the midgut epithelium at a distance of about 0.2–0.8 μm. After repletion, the peritrophic membrane becomes thicker and thicker and more and more winding and simultaneously becomes multi-layered mainly in its arched parts. The distance between the peritrophic membrane and the midgut epithelium increases considerably and in the arched parts can reach as much as about 13 and 16 μm in metamorphosing larvae and nymphs, respectively and 25 μm in ovipositing females.
  • Publication
    Accès libre
    Rickettsia conorii isolated from Rhipicephalus sanguineus introduced into Switzerland on a pet dog
    (1984)
    Peter, Olivier 
    ;
    Burgdorfer, Willy
    ;
    Aeschlimann, André 
    ;
    Chatelanat, P.
    A tick/rickettsial survey in a household near Geneva, Switzerland, revealed that 30 (40%) of 75 nymphs and adults of the brown dog tick, Rhipicephalus sanguineus, were infected with a rickettsial agent biologically and antigenically indistinguishable from R. conorii, the causative agent of boutonneuse fever. Introduced in 1976 from either southern France of Italy by the family''s pet dog, the tick infestation had steadily increased until 1981 when control measures were initiated. During 1980 and 1981, four persons associated with the household''s pet dog contracted a febrile illness diagnosed as boutonneuse fever.
  • Publication
    Accès libre
    Ecologie et éthologie d'Ixodes Ricinus L. en Suisse. Quatrième note : Comparaison de deux populations d’altitude différente
    (1975)
    Mermod, Claude
    ;
    Aeschlimann, André 
    ;
    Graf, Jean-François
    Un échantillonnage des Tiques fixées sur Micromammifères a ete effectué en 1974-1975 dans une station d'altitude moyenne (830 m). Les résultats sont comparés à ceux précédemment obtenus dans une station de plaine (430 m)., A sampling of the ticks on small mammals was made in a middle altitude station (830 m). Results were compared with those obtained in a lowland station (430 m).
  • Publication
    Accès libre
    Prävalenz der Lyme-Borreliose in einer schweizerichen Risikopopulation
    (1988)
    Fahrer, Heinz
    ;
    van der Linden, Sjef M.
    ;
    Sauvain, Marie-Josephe
    ;
    Gern, Lise 
    ;
    Zhioua, Elyes
    ;
    Aeschlimann, André 
    L'épidémiologie de la borréliose de Lyme n'est pas encore suffisamment connue. La signification d'un litre d'anticorps positif n'est pas claire. Nous avons abordé ces deux questions en étudiant un grand groupe de coureurs d'orientation en Suisse car ils sont en contact étroit avec les biotopes habités par les tiques. - Nos chiffres prouvent que la prévalence de titres positifs d'anticorps est haute mais que la prévalence de symptômes est basse. Ces résultats établissent qu'une proportion importante des infections à Borrelia burgdorferi se déroule de manière asymptomatique. Un titre d'anticorps isolé, même très positif, n'a pas de valeur diagnostique., Die Epidemiologie der Lyme-Borreliose in Europa ist noch ungenügend bekannt, ebenso die Bedeutung positiver Antikörpertiter. Anhand eines grossen Kollektivs schweizerischer Orientierungsläufer, einer Bevölkerungsgruppe mit besonders engem Kontakt zu zeckenbewohnten Biotopen, suchten wir eine Annäherung an verschiedene der noch offenen Fragen. - Bei 964 regelmässig im Wald orientierungslaufenden gesunden Probanden fanden sich mittels Immunfluoreszenztechnik bei rund 20% auf eine Infektion hinweisende Antikörper vom IgG-Typ gegen Borrelia burgdorferi, bei rund 4% Antikörper vom IgM-Typ. Selbst bei hochtitrig positiven Individuen konnten jedoch in nur sehr wenigen Fällen aktuelle oder anamnestische Erkran- kungssymptome nachgewiesen werden. Die Läuferpopulation wird serologisch und klinisch weiterverfolgt. - Unsere Resultate zeigen in dieser Risikogruppe eine recht hohe Antikörper-, hingegen eine geringe Erkrankungsprävalcnz. Sie belegen den offensichtlich hohen Anteil klinisch stumm verlaufender Infektionen mit Borrelia burgdorferi. Ein einzelner, selbst hoher Antiborrelientiter ist diagnostisch nicht verwertbar., The epidemiology of "Lyme borreliosis" in Europe and the significance of positive antibody tilers against Borrelia burgdorferi is not well known. Since "orienteering", a competitive cross country sport with a map and a compass, usually in forests, elevates the risk of being bitten by ticks and infected by B. burgdorferi, nearly 1000 orienteerers were included in a prospective study. - In this population the prevalence of positive IgG-antibodies (immunofluorcscence technique) was almost 20% and of IgM-antibodies 4%. However, the frequency of associated symptoms in the clinical history of the pro- bands was very low, even in individuals with highly positive liters. - We conclude that the rate of asymptomatic Borrelia infections is high in this special group, and probably also in the general population, and that one has therefore to be cautious in interpreting an isolated positive "Lyme titer". Further investigations are needed, and, in particular, follow-up of the many "positive" subjects without clinical symptoms may be helpful in under- standing this fascinating disease better.
  • Publication
    Accès libre
    The early Embryonic Development of the Argasid tick Ornithodorus moubata (Acarina: Ixodoidea: Argasidae)
    (1988)
    Fagotto, François
    ;
    Hess, Ernst
    ;
    Aeschlimann, André 
    The mode of cleavage of the centrolecithal tick eggs has so far been considered to be superficial. Evidence could be obtained from an electron-microscopic study of Omithodoros moubata Murray 1877 that cleavage of this species is total. The early development leads to a diploblastic stage composed of a superficial layer of yolk-free micromeres (ectomesoderm) and a core of yolk-rich macromeres (primary entoderm).