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Gern, Lise
Résultat de la recherche
Multi-strain infections of the Lyme borreliosis pathogen in the tick vector
2017, Durand, Jonas, Herrmann, C., Genné, D., Sarr, Anouk, Gern, Lise, Voordouw, Maarten
Protozoan and bacterial pathogens in tick salivary glands in wild and domestic animal environments in South Africa
2014, Berggoetz, M, Schmid, M, Ston, D, Wyss, V, Chevillon, Christophe, Pretorius, A-M, Gern, Lise
Borrelia burgdorferi genospecies detection by RLB hybridization in Ixodes cinus ticks from different sites of North-Eastern Poland
2014, Dunaj, Justyna, Zajkowska, JM, Kondrusik, M, Gern, Lise, Rais, Olivier, Moniuszko, Anna, Pancewicz, Slawomir, Swierzbi?ska, R
Do ticks and Borrelia burgdorferi s.l. constitute a burden to birds?
2013-1-1, Norte, C.A., Lobato, D.C., Braga, E., Antonelli, Y., Lacorte, G., Félix, G.M., Gonçalves, M., Lopes de Carvalho, I., Gern, Lise, Núncio, M.S., Ramos, J.A.
Genetic variation in transmission success of the Lyme borreliosis pathogen Borrelia afzelii
2015, Tonetti, Nicolas, Voordouw, Maarten, Durand, Jonas, Monnier, Séverine, Gern, Lise
The vector-to-host and host-to-vector transmission steps are the two critical events that define the life cycle of any vector-borne pathogen. We expect negative genetic correlations between these two transmission phenotypes, if parasite genotypes specialized at invading the vector are less effective at infecting the vertebrate host and vice versa. We used the tick-borne bacterium Borrelia afzelii, a causative agent of Lyme borreliosis in Europe, to test whether genetic trade-offs exist between tick-to-host, systemic (host-to-tick), and a third mode of co-feeding (tick-to-tick) transmission. We worked with six strains of B. afzelii that were differentiated according to their ospC gene. We compared the three components of transmission among the B. afzelii strains using laboratory rodents as the vertebrate host and a laboratory colony of Ixodes ricinus as the tick vector. We used next generation matrix models to combine these transmission components into a single estimate of the reproductive number (R0) for each B. afzelii strain. We also tested whether these strain-specific estimates of R0 were correlated with the strain-specific frequencies in the field. We found significant genetic variation in the three transmission components among the B. afzelii strains. This is the first study to document genetic variation in co-feeding transmission for any tick-borne pathogen. We found no evidence of trade-offs as the three pairwise correlations of the transmission rates were all positive. The R0 values from our laboratory study explained 45% of the variation in the frequencies of the B. afzelii ospC strains in the field. Our study suggests that laboratory estimates of pathogen fitness can predict the distribution of pathogen strains in nature.
Tick-borne pathogens in the blood of wild and domestic ungulates in South Africa: interplay of game and livestock
2014, Berggoetz, M, Schmid, M, Ston, D, Wyss, V, Chevillon, Christophe, Pretorius, A-M, Gern, Lise
Species co-occurrence patterns among Lyme borreliosis pathogens in the tick vector Ixodes ricinus
2013-1-1, Herrmann, Coralie, Gern, Lise, Voordouw, Maarten
Tick-borne pathogens in ticks collected from breeding and migratory birds in Switzerland
2014-11-17, Lommano, Elena, Dvorak, Charles, Vallotton, Laurent, Jenni, Lukas, Gern, Lise
Prevalence and phylogenetic analysis of tick-borne encephalitis virus (TBEV) in field-collected ticks (Ixodes ricinus) in southern Switzerland
2014, Rieille, Nadia, Bressanelli, Stephane, Freire, Caio C. M., Arcioni, Severine, Gern, Lise, Peter, Olivier, Voordouw, Maarten
Ixodes ricinus ticks infected with the causative agent of Lyme disease, Borrelia burgdorferi sensu lato, have higher energy reserves
2013-1-1, Herrmann, Coralie, Voordouw, Maarten, Gern, Lise