Tandem Reactions Combining Diels-Alder Reactions with Sigmatropic Rearrangement Processes and their Use in Synthesis

Diels-Alder reactions and sigmatropic rearrangements are of paramount importance in synthesis. The tandem Diels-Alder/sigmatropic rearrangement processes combining these two powerful methods is presented in this review. Both possible sequences of this tandem process are discussed and several successful examples of the synthesis of natural products using the combination of these two reactions as key step demonstrate the utility of these processes.