The tick blood meal: From a living animal or from a silicone membrane?
Date issued
2007
In
Altex-Alternativen Zu Tierexperimenten
No
24
From page
39
To page
41
Subjects
reduction replacement veterinary drugs tick diagnostic parasite ectoparasites
Abstract
An artificial feeding unit with a reinforced silicone membrane to replace host skin provides ticks with a perch over blood with a tick attachment rate of 75-100%. Some 5 mg of an acaricide like fipronil is sufficient to establish survival curves over different doses down to ppb levels in blood. This in vitro feeding assay for hard ticks is more advantageous than in vivo trials on animals.
Publication type
journal article