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Novel bioconjugates of aminolevulinic acid with vitamins
Auteur(s)
Date de parution
2008
In
Org. Lett.
Vol.
20
No
10
De la page
4453
A la page
4455
Résumé
5-Aminolevulinic acid (ALA) and derivs. thereof have been successfully used in photodynamic cancer therapy (PDT). The synthesis of novel bioconjugates combining ALA with two lipophilic and one hydrophilic vitamins is reported. The new bioconjugates allow studying the potential synergies between the two components in PDT. The synthetic methodol. is robust giving the bioconjugates in good to satisfactory yield. [on SciFinder(R)]
Type de publication
Resource Types::text::journal::journal article