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  • Publication
    Accès libre
    Tandem Reactions Combining Diels-Alder Reactions with Sigmatropic Rearrangement Processes and their Use in Synthesis
    (1998)
    Neuschütz, Klaus
    ;
    Velker, Jörg
    ;
    Diels-Alder reactions and sigmatropic rearrangements are of paramount importance in synthesis. The tandem Diels-Alder/sigmatropic rearrangement processes combining these two powerful methods is presented in this review. Both possible sequences of this tandem process are discussed and several successful examples of the synthesis of natural products using the combination of these two reactions as key step demonstrate the utility of these processes.
  • Publication
    Métadonnées seulement
    Preparation of N-alkylketene-N-butadienyl-N,O-silyl acetals
    (1996)
    Franz, Andreas
    ;
    Eschler, Pierre Yves
    ;
    Tharin, Manuel
    ;
    ;
    The synthesis of a series of dienamides 5a-j using Oppolzer's method is described. Using Rathke's method the ketene N,O-silyl acetals 6a-j can be obtained in good yield from the corresponding dienamides. The ketene acetals are obtained free of base and free of salts. They are stable and can be stored at - 20 degrees C. The new dienes are useful reagents for tandem reactions.
  • Publication
    Accès libre
    Preparation of N-Alkylketene-N-Butadienyl-N,O-Silyl Acetals
    (1996)
    Franz, Andreas
    ;
    Eschler, Pierre-Yves
    ;
    Tharin, Manuel
    ;
    ;
    The synthesis of a series of dienamides 5a-j using Oppolzer’s method is described. Using Rathke’s method the ketene N,O-silyl acetals 6a-j can be obtained in good yield from the corresponding dienamines. The ketene acetals are obtained free of base and free of salts. They are stable and can be stored at -20°C. The new dienes are useful reagents for tandem reactions.