Supramolecular Self-Assemblies Incorporating Arene Ruthenium Complexes
| Responsable du projet | Bruno Therrien |
| Collaborateur | Mona Anca Furrer |
| Résumé |
Introduction of transition metal in the self-assembly of discrete
supramolecular structures has recently received a great attention.
Both, two- and three-dimensional structures, are found in the
literature and the interest in these complex systems lie in the
scientific field of chemistry (recognition and selective
transformations), biology (translocation of drugs across membranes,
biomimetics), and material science (construction of macroscopic
architectures and devices at the molecular level). Their synthesis
involves a directional-bonding approach in which the metal centres,
the multibranched ligands, or a combination of both, control the
geometric shapes or polyhedra of the resulting assemblies. When
systems containing ruthenium atoms in a two-dimensional fashion are
relatively common, three-dimensional structures incorporating
ruthenium atoms are scarce. This project originates from the
introduction of arene ruthenium building blocks in the
self-assembly with 2,4,6-tri(pyridyl)-1,3,5-triazine subunits of
hexanuclear metalloprisms. The synthesis of these new
metalla-prismatic compounds have opened a wide perspective for bio-
and nano-applications and therefore this research project intends to
exploit the potential of arene ruthenium moieties in self-assemblies
in order to design nano-structured molecules such as supramolecular
squares and rectangles, chiral triangular prisms and supramolecular
host-guest systems. |
| Mots-clés |
Supramolecular Assemblies, Arenes, Ruthenium, Bioinorganic, Anticancer Agents, Supramolecular chemistry, Drug delivery |
| Type de projet | Recherche fondamentale |
| Domaine de recherche | Chimie inorganique |
| Source de financement | FNS - Encouragement de projets (Div. I-III) |
| Etat | Terminé |
| Début de projet | 1-10-2010 |
| Fin du projet | 30-4-2012 |
| Budget alloué | 143'946.00 |
| Autre information |
http://p3.snf.ch/projects-129518# |
| Contact | Bruno Therrien |