Synthesis, characterization and exploration of the catalytic, supramolecular and biological applications of dinuclear complexes
Author(s)
Johnpeter, Justin Paul Raj
Editor(s)
Date issued
2013
Subjects
Carbonyl ligands Carboxylato bridges Fatty acids Dinuclear complexes Ruthenium Rhodium Iridium Fluorinated fatty acids Supercritical carbon dioxide Molecular recognition Porphyrin tweezers Pyrene tweezers Supramolecular chemistry Multinuclear complexes Photosensitizers Porphyrin ligand Bio-organometallic Photodynamic therapy Biologically active acids
Abstract
The work presented in this thesis involves the synthesis and characterization of dinuclear ruthenium, rhodium and iridium complexes. The catalytic, supramolecular and biological applications of these dinuclear complexes will be discussed. In the first part, the synthesis of sawhorse-type diruthenium tetracarbonyl complexes and their catalytic applications in the supercritical carbon dioxide (scCO<sub>2</sub>) are presented. Synthesis of sawhorse-type molecular tweezers derived from pyrenyl and porphyrin carboxylic derivatives are presented in the second part. The host-guest interactions between the sawhorse-type molecular tweezers with different guest molecules will be discussed. In the final part, the anticancer potential of dinuclear ruthenium, rhodium and iridium complexes are evaluated with different cancer cell lines.
Notes
Thèse de doctorat : Université de Neuchâtel, 2013
Publication type
doctoral thesis
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