Transporting and Shielding Photosensitisers by Using Water-Soluble Organometallic Cages: A New Strategy in Drug Delivery and Photodynamic Therapy
Author(s)
Date issued
2013
In
Chem. - Eur. J.
Vol
26
No
19
From page
8378
To page
8386
Subjects
review cancer PDT photosensitizer drug delivery skin
Abstract
A review. Skin photosensitivity remains one of the main limitations in photodynamic therapy. In this Concept article a strategy to overcome this limitation is described, in which the photosensitizer is hidden inside the hydrophobic cavity of a water-sol. organometallic cage. The metallacage not only protects the photosensitizer from light, it also facilitates its delivery to cancer cells. [on SciFinder(R)]
Publication type
journal article