Highly Efficient NMR Enantiodiscrimination of Chiral Octanuclear Metalla-Boxes in Polar Solvent

Detection of the molecular chirality of a series of octanuclear metalla-boxes can be readily achieved using the NMR chiral solvating agent Λ-BINPHAT in CD₃CN: only 0.05 to 0.10 equiv being necessary for a complete baseline separation of some of the proton signals.