Macrocyclisation of 2-(5-(2-hydroxyethyl)furan-2-yl)acetic acid model compounds of nonactic acid

Author(s)
Eng, Carine
Simone, Jean-Mary
Hartenbach, Akane
Loiseau, François
Date issued
2009
In
Monatshefte für Chemie / Chemical Monthly, Springer, 2009/140/3/349-354
Subjects
Heterocycles Macrocycles Natural product analogues Nonactin Protecting groups
Abstract
The macrocyclisation of hydroxyethylfuranyl acetic acid and of dehydrogenated model compounds of nonactic acid was investigated to develop a facile synthesis of nonactin analogues. By applying the Yamagushi macrocyclisation to our ω-hydroxyacids, we were able to isolate a mixture of di-, tri-, tetra- and pentameric macrocycles.
Publication type
journal article
Identifiers
https://libra.unine.ch/handle/20.500.14713/61161
DOI
10.1007/s00706-008-0031-4
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