Titration-on-a-chip, chemical sensor–actuator systems from idea to commercial product
Author(s)
van der Schoot, Bart
van der Wal, Peter
de Rooij, Nicolaas F.
West, Steve
Date issued
2005
In
Sensors and Actuators B: Chemical, Elsevier, 2005/105/1/88-95
Subjects
Sensor–actuator devices Acid–base titration Solid-state transducer Coulometric titration ISFET
Abstract
The earliest reports of integrated chemical sensor–actuator devices to perform coulometric acid–base titrations date back almost 20 years. Recently a first commercial instrument appeared that allows to perform very rapid, accurate acid–base determinations with a solid-state probe and no need for liquid titrants. This paper reviews some of the early developments and shows the effort that has been undertaken to bring this technology to routine use in the analytical laboratory and beyond.
Publication type
journal article
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