Sesquiterpene constituents in Petasites hybridus.
Author(s)
Date issued
April 2002
In
Phytochemistry
Vol
59
No
8
From page
795 p.
To page
803 p.
Subjects
Petasites hybridus Sesquiterpene hydrocarbons Petasitene Albene Pethybrene Chemical correlation
Abstract
The essential oil of the rhizomes of Petasites hybridus (Asteraceae) was investigated by gas chromatography, mass spectrometry, 1- and 2-dimensional NMR techniques and chemical correlations. Two new sesquiterpene hydrocarbons, petasitene and pethybrene, could be identified. Petasitene is the parent sesquiterpene hydrocarbon to the known norsesquiterpene albene. The absolute configuration of petasitene could be assigned by conversion of natural albene to petasitene by partial synthesis. Pethybrene is a tricyclic sesquiterpene hydrocarbon, which rearranges to the structurally related alpha-isocomene under acidic conditions. Several sesquiterpenes were isolated from the hydrodistillation products of Petasites hybridus and investigated by spectroscopic methods and chemical correlations
ISSN
0031-9422
Publication type
journal article
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