The synthesis of a pyrazol analogon of porphobilinogen with the help of the Mukaiyama aldol reaction
Author(s)
Chaperon, André
Bertschy, Hugo
Franz-schrumpf, Anne-laurence
Hugelet, Bertrand
Neels, Antonia
Date issued
2003
In
Chimia
Vol
10
No
57
From page
601
To page
606
Subjects
Aldol condensation (Mukaiyama prepn. of a pyrazol analogon of porphobilinogen from levulinates via a Mukaiyama aldol reaction) porphobilinogen pyrazol analog prepn Mukaiyama aldol porphobilinogen pyrazol analog prepn
Abstract
The synthesis of a pyrazol analogon of porphobilinogen is described. The Mukaiyama crossed aldol reaction is the key step of our approach. The retrosynthetic anal. follows the mechanism for the biosynthesis of porphobilinogen initially proposed by Shemin. [on SciFinder(R)]
Publication type
journal article