Options
Radical Couplings as Key Steps for the Preparation of Derivatives of Nonactic Acid
Auteur(s)
Date de parution
2007
In
Monatsh. Chem.
Vol.
2
No
138
De la page
121
A la page
129
Résumé
Free radical couplings from furan, as cheap starting material, were studied in view of developing a rapid strategy en route to the synthesis of derivs. of nonactin. The chain contg. the alc. function was introduced in one or two steps in 86% yield. For the introduction of the second chain with the ester function two different coupling methods were tested. Starting from the advanced intermediates obtained by this method, nonactin analogs, such s I (R = CMe3, CH2Me), were prepd. by catalytic hydrogenation of the furan ring. [on SciFinder(R)]
Type de publication
Resource Types::text::journal::journal article
