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Stoeckli-Evans, Helen
Nom
Stoeckli-Evans, Helen
Affiliation principale
Email
helen.stoeckli-evans@unine.ch
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Voici les éléments 1 - 2 sur 2
- PublicationMétadonnées seulementRac-(2R*,3R*)-S-Ethyl-4-Chloro-3-Hydroxy-2-Phenylbuthanethioate and Rac-(2R*,3R*)-S-Ethyl-2-Phenyl-3-(tosyloxy)buthanethioate: Dichotomy of the Stereoselectivity of the Mukaiyama Reaction(2010)
; ; The compds., rac-(2R*,3R*)-S-ethyl-4-chloro-3-hydroxy-2-phenylbuthanethioate (I) and rac-(2R*,3R*)-S-ethyl-3-hydroxy-2-phenylbuthanethioate (II), were prepd. by the Mukaiyama crossed aldol reaction between the silyl enol ether of S-Et 2-phenylethanethioate and simple aldehydes, like 2-chloroacetaldehyde (for I) and acetaldehyde (for II). The stereoselectivity of the Mukaiyama aldol reaction has switched from a syn selective process for the reaction using 2-chloroacetaldehyde to an anti selective process for the reaction with acetaldehyde. [on SciFinder(R)] - PublicationMétadonnées seulementrac-Methyl 4-azido-3-hydroxy-3-(2-nitrophenyl)butanoate(2009)
; ; In the title compd., C11H12N4O5, the mean plane through the nitro substituent on the benzene ring is inclined to the benzene mean plane by 85.8 (2)°, which avoids steric interactions with the ortho substituents. The hydroxy group is involved in bifurcated hydrogen bonds. The first is an intramol. O-H...O hydrogen bond, involving the ester carbonyl O atom, which gives rise to the formation of a boat-like hydrogen-bonded chelate ring. The second is an intermol. O-H...N hydrogen bond involving the first N atom of the azide group of a symmetry-related mol. In the crystal structure this leads to the formation of a polymer chain extending in the c-axis direction. Crystallog. data are given. [on SciFinder(R)]